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Uh-oh! Might this have anything to do with the cheating rumors surrounding her hubby Jesse James?

Sandra Bullock planned to attend the London premiere (and junket) of The Blind Side next week - she just won an Oscar for her role - but suddenly canceled her trip unexpectedly...

A rep at Warner Bros. has confirmed that she is "unable to travel due to unforeseen circumstances."

Meanwhile, Sandra's husband Jesse has been accused of cheating on the actress with a tattoo model. According to the report, Jesse and the woman carried on an eleven-month affair which included "five weeks of sex."

Will Sandra and co. be making a statement about all this?