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George Clooney and Elisabetta Canalis have ended their almost-two-year relationship.

"We are not together anymore. It's very difficult and very personal, and we hope everyone can respect our privacy," the couple said in a joint statement released Wednesday.

They were last seen together in May for the actor's star-studded 50th birthday celebration.

Only a few weeks ago, 32-year-old Canalis told Italian magazine Chi that she was "very happy" with her man, but also said, "I am a firm believer in marriage, in the future I will be married ..."

Clooney has confirmed several times over the years that he will not marry again (he was married once in the early '90s).