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Oscar winners Anne Hathaway and Reese Witherspoon were looking absolutely fab last night at the Hollywood Stands Up To Cancer Event, which was hosted by Reese and husband Jim Toth. Lookin' good ladies!

Anne opted for an upscale casual ensemble consisting of an edgy studded blazer, black t-shirt and embellished, pointed toe heels. There's been a lot of talk of The "Les Miserables" star's style since she recently split with celebrity stylist Rachel Zoe. This event is Anne's first appearance with rumored new stylist Penny Lovell -- and we think the new duo knocked it out of the park with this one. This could be the beginning of a beautiful partnership!

Meanwhile, Reese was bright and bold in her low-cut orange Roland Mouret dress. The mother-of-three added simple touches with gold stilettos, a bracelet and drop earrings along with her wedding and engagement rings.

The gals joined Heidi Klum, Selena Gomez, Christina Aguilera, Gwyneth Paltrow and Diane Kruger at the glittering charity event.

reese-sutc-460.jpgGetty Images for Entertainment Industry Foundation

Elusive couple Katy Perry and John Mayer even made an appearance at the event. In fact, Jennifer Aniston, who usually helps man the phones, was noticably absent. Maybe because of her ex? Geez -- she can't attend any events anymore ... all the awards shows are out because Brad will be there and now she can't even support her favorite charity because she'll run into John? Yeesh!