She's leaving no prisoners! Kicking off the first episode of Fashion Police since the sudden death of Joan Rivers, new host Kathy Griffin is skewering the unskewerable -- Amal Alamuddin.

Here's a hit list of our favorite jabs at George Clooney's notable wife:

- "Yeah, she’s annoying …You heard me! Everybody run in fear! I thought it was weird she had those gloves that remind me of, like, a porn scene, where the guy goes home and there’s the naughty dishwasher and she only has the gloves."

-- The gloves looked like they should be "on a vet helping a calf be born."

-- "Like, she used those bovine insemination gloves to rake through her hair instead of a brush. I'm fascinated how we’re like, not supposed to make fun of her because she married the great George Clooney. Look, everybody’s on the table, George! Nobody's safe, nobody gets a pass."

And of course we loved Kathy's ode to the divine Miss Rivers:

-- "Before I start making more enemies and burning new bridges, I want to thank my good friend, [Joan Rivers]. Joan, I know you are watching from heaven, but I am not afraid to bring the hammer down on anyone."

Joan would be so proud of the fiery redhead's inaugural show!