Getty Images for Smart Water

Best "Friends" Jennifer Aniston and Courteney Cox reunited for an event at St Jude's Children's Hospital at the W hotel in Los Angeles on Tuesday night.

Jennifer, who has been a longtime supporter of the children's charity, was the night's host, wearing an Isabel Marant Ikat-Print Tehora Dress, priced at $745.

Courteney dressed down for the event, wearing a beige sweater and black slacks.

While we love that the two are besties offscreen -- we sure would love to see them team up onscreen again! Rachel and Monica Take Miami?!

The event, which was sponsored by Smartwater, had a number of Hollywood's hotties in attendance including Emma Roberts, Joanna Garcia, Jamie-Lynn Sigler and Geoff Stults.