President Jolie?!

Angelina Jolie used to wear her partner's blood in a vial around her neck and make out with her brother on the Oscars red carpet. Now she's got 20 years under her belt as a United Nations ambassador and six children in her brood and people are wondering ... would she ever run for political office?

Well, People magazine asked her that question and she said ... drumroll ... "Never say never." Never say never! She quoted Justin Bieber and gave fans hope that SHE could be the next state representative of California, the next mayor of Los Angeles, or the next President of the United States even!

Okay -- here's the FULL quote from the 43-year-old humanitarian/actress: "Never say never,. [But ] right now I am looking to others for leadership."

So who'll she vote for in 2020? Well, she didn't answer that, but she said the causes that are important to her are women's empowerment and a proposal for a permanent international body to investigate war crimes. "If you look across the world, there are far too many women and girls who are not only not seeing progress, their rights are slipping away from them. We have to change laws that treat women as second-class citizens," she told the mag.

Meanwhile, she's also focused on her duties as a mother, including seeing her oldest child Maddox off to college in the fall. She hasn't disclosed what institution he'll be attending, but the two were spotted visiting colleges in South Korea late last year.